2015 southern hemisphere influenza season

Testimony of karen midthun, fda, hearing on examining the u. Influenza a virus subtype h3n2 ah3n2 is a subtype of viruses that causes influenza flu. Following a severe winter epidemic of drifted influenza ah3n2 during januarymarch 2015, the hong kong government purchased vaccines of southern hemisphere formulation for administration prior to the anticipated summer influenza epidemic. Sanofi pasteur ships first 20152016 seasonal influenza vaccine doses in united states leading influenza vaccine manufacturer to distribute more than 65 million doses to help protect people six months and older against the flu direct shipments to health care providers and distributors marks the start of the influenza immunization season.

Seasonal influenza 2015 2016 in the eueea countries. Since the 2012 season, the who recommendations have also included the formulation of an. In another study conducted in 635 month olds during the 2014 2015 and 2015 2016 northern hemisphere and 2014 and 2015 southern hemisphere influenza seasons, iiv4 ve was 51% 97% ci. Influenza epidemiology and influenza vaccine effectiveness. Starting in the 201220 season, the recommendation shifted from a trivalent influenza vaccine tiv containing three strains to a quadrivalent influenza vaccine qiv that contains both influenza b lineages. It is recommended that quadrivalent vaccines for use in the 2020 southern hemisphere influenza season contain the following. Mar 06, 2015 annual study to investigate inactivated subunit influenza vaccine due to new virus strains for the southern hemisphere 2015 season the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. What is the recommended composition of influenza virus vaccines for use in the 201819 northern hemisphere influenza season. Australias flu season is just winding up it enters spring. In chile, ah1n1pdm09 was more prevalent, while in colombia both a subtypes were codominant. Oct 07, 2014 the recommendation for the bvictorialineage vaccine component has not changed in comparison to the recommendation for the northern hemisphere 2014 2015 influenza seasonal vaccine recommendation 3 or for the 2014 southern hemisphere influenza season 4.

The recommendation for the bvictorialineage vaccine component has not changed in comparison to the recommendation for the northern hemisphere 20142015 influenza seasonal vaccine recommendation 3 or for the 2014 southern hemisphere influenza season 4. Texas influenza surveillance report 20142015 season2015. Influenza activity united states, 201415 season and. Sep 21, 2017 the season in the southern hemisphere has been dominated by the h3n2 virus. After vaccination, it takes about two to three weeks for antibodies to develop in the body and provide protection against influenza virus infection. The southern hemisphere influenza and vaccine effectiveness research and. Maryland influenza plan 20182019 influenza season updated october 5, 2018 3 maryland department of health i. In the temperate zone of the northern hemisphere a sharp decline of influenza activity was observed in recent weeks while in the temperate zones of the southern hemisphere, influenza season has not started yet. Who switches h1n1 in southern hemisphere flu vaccine. The start of the primary influenza season was not ascertainable for kenya and malaysia table 2. There is a new h3n2 strain, and a switch from the victoria b lineage virus back to a yamagata b lineage virus for trivalent vaccines. Apr 27, 2015 new zealand nz is a temperate southern hemisphere country with a population of 44 million people. Bad flu season in southern hemisphere could be a harbinger.

Influenza flu is a contagious respiratory illness caused by the influenza virus. Phylogenetic data from the northern hemisphere suggested that the ah3 component of the 2015 tiv may not be ideally matched and ve estimates for australia were indeed low to moderate for ah3n2 ve 44%. Texas influenza laboratory data and influenzalike illness ili indicators demonstrated a minor decrease compared to last week. Determination of predominance of influenza virus strains. The percentage of specimens positive for influenza decreased compared to last week. Recommended composition of influenza virus vaccines for use. Our estimates are similar to those from the 20152016 northern hemisphere influenza season formulation of 1048%, and the 2015 southern hemisphere formulation of 54%. The newly recommended h1n1 vaccine strain, called amichigan452015 replaces. The southern hemisphere influenza and vaccine effectiveness research and surveillance shivers project, a 5year 20122016 multiagency and multidisciplinary collaboration, aims to measure. Therefore, residents are advised to receive the 2015. Who recommendation for the 2020 southern hemisphere influenza vaccines. In hong kong, which has a humid subtropical climate, the flu season runs from december to march, in the winter and early spring. The season in the southern hemisphere has been dominated by the h3n2 virus.

Intraseason decline in influenza vaccine effectiveness during. Immunogenicity and safety of southern hemisphere inactivated quadrivalent influenza vaccine. Recommended composition of influenza virus vaccines for. Influenza activity can sometimes be predicted and even tracked geographically. The 201516 northern hemisphere influenza vaccine had the same composition as the 2015 southern hemisphere vaccine. Sep 29, 2016 for quadrivalent vaccines containing two influenza b strains, the who experts recommended adding phuket307320like virus, a yamagata lineage virus that was the second b component of quadrivalent vaccines for both the southern hemisphere s current season and the northern hemisphere s 2015 16 season. It is recommended that trivalent vaccines for use in the 2015 influenza season southern hemisphere winter contain the following. The season occurs during the cold half of the year in each hemisphere. During the northern hemispheres previous flu season, some flu experts in. Health, general immunogenetics research influenza vaccines safety and security measures.

The timing of primary peaks obtained from the 20102014 influenza virus circulation time series of each country relative to their capital cities latitude is shown in fig. Pooling and the potential dilution of repeat influenza. The following is a list of who recommended strains for the northern hemisphere influenza season. Influenza activity remains elevated across the state of texas, but it is decreasing. For quadrivalent vaccines that contain two influenza b strains, who experts recommend adding brisbane602008like virus, a victorialineage virus what was a component of trivalent versions of the southern hemispheres current vaccine as well as the northern hemispheres 201718. Introduction influenza also known as the flu is a contagious respiratory illness caused by the influenza virus. It is recommended that trivalent vaccines for use in the 2016 influenza season southern hemisphere winter contain the following.

Influenza activity peaked during late december, with influenza a h3n2 viruses predominant early in the season through the week ending february 21, 2015 week 7. In 2015, a seroepidemiological study will use a sample of patients from the. The following is a list of who recommended strains for the southern hemisphere influenza season. Review of global influenza activity, october 2015 october 2016. Flu season is an annually recurring time period characterized by the prevalence of outbreaks of influenza flu. While influenza viruses circulate yearround, most of the time flu activity peaks between december and february, but activity can last as late as may. Seasonal influenza activity, 6 september 2015 6 february 2016 between 6 september 2015 and 6 february. Who recommended composition of influenza virus vaccines for. In the northern hemisphere, flu season can begin as early as october and last as late as may. The risk for exposure to influenza during travel depends somewhat on the time of year and destination. Who made its recommendations for the 2015 southern hemisphere influenza vaccine on september 25, 2014, by which time these drifted h3n2 viruses were common, prompting a recommended change in the upcoming southern hemisphere vaccine composition.

Generally, cambodian seasonal influenza virus isolates matched the southern hemisphere trivalent inactivated influenza vaccine tiiv formulations during the relevant year they were released table 2. Effectiveness of seasonal influenza vaccine in australia. One human infection with a novel influenza a virus was reported by the state of ohio. One reformulation of the influenza vaccine is for the northern hemisphere, and the other is for the southern hemisphere.

Influenza virus strains perennially circulate throughout the world. Who released the recommended composition of influenza virus vaccines for use in the 20192020 northern hemisphere influenza season. Circulation and characterization of seasonal influenza. The flu virus can cause mild to severe illness and at times can lead to death. Texas influenza surveillance report 20142015 season2015 mmwr week 14 april 05, 2015 april 11, 2015 report produced on 4172015. Influenza b became the predominant virus starting week 8 the week ending february 28, 2015. Department of health influenza viruses received and tested. Sanofi pasteur ships first 20152016 seasonal influenza. Who collaborating centre for influenza recent news. This recommendation relates to the influenza vaccines for the forthcoming influenza season in the southern hemisphere 2015. Recommend annual influenza vaccination to your patients help prevent the potentially devastating effects of influenza in your community the southern hemisphere influenza and vaccine effectiveness, research and surveillance shivers serosurvey, in 2015, provided information about the immunity that people in the community have against influenza. Results from the global influenza hospital surveillance network. Testimony of karen midthun, fda, hearing on examining the. Southern hemisphere influenza and vaccine effectiveness.

Review of global influenza activity, october 2016october 2017. Pdf southern hemisphere influenza and vaccine effectiveness. Recommended composition of the australian influenza vaccine. Flu vaccine changes for the 2019 southern hemisphere vax. Recommended composition of the australian influenza vaccine for the 2015 season. This report summarizes influenza activity in the united states during the 201415 influenza season september 28, 2014may 23, 2015 and reports the recommendations for the components of the 201516 northern hemisphere influenza vaccine. For the 2015 influenza season, the tga has registered nine vaccines which will be available for use in the following age groups.

The recommendation for the bvictorialineage vaccine component has not changed in comparison to the recommendation for the northern hemisphere 2014 2015 influenza seasonal vaccine recommendation 3 or for the 2014 southern hemisphere influenza season 4. Immunogenicity and reactogenicity of glaxosmithkline gsk biologicals quadrivalent split virion influenza vaccine fluarix tetra 2015 season southern hemisphere in adults 18 years of age and above the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Overall, peak influenza circulation patterns in temperate countries were well aligned with the winter season mostly between january and february in the northern hemisphere blue and green circles above the. When to receive 2015 southern hemisphere seasonal influenza vaccination in hong kong, summer influenza season usually comes in july or august. Flu seasons also exist in the tropics and subtropics, with variability from region to region.

Who swaps out h3n2, b strains in southern hemisphere flu. Who switches h1n1 in southern hemisphere flu vaccine cidrap. A michigan 452015 h1n1pdm09like virus ahong kong48012014 h3n2like virus bbrisbane602008like virus. Influenza activity us and worldwide, may 24sept 5, 2015. However, yearround circulation was also described, characteristic of influenza seasonality in tropical. Immunogenicity and reactogenicity of glaxosmithkline gsk. Recommended composition of influenza virus vaccines for use in the 2015 southern hemisphere influenza season 25 september 2014. The number of influenza cases in parts of the southern hemisphere has spiked early this season, according to latest indicators media reports from areas of australia in the past week have. Review of global influenza activity, october 2015october 2016. New zealand nz is a temperate southern hemisphere country with a population of 44 million people. A recommendation will be made in february 2015 relating to vaccines that will be used for the influenza season in the northern hemisphere 20152016. West africa stretching from senegal to the central african republic and south africa showed a seasonality pattern that was similar to that seen in the temperate regions of the southern hemisphere. For quadrivalent vaccines that contain a second b strain, the agency recommended adding phuket307320like virus, a yamagata lineage virus that was the b component of trivalent vaccines for the southern hemispheres current season and is the b component of trivalent vaccines for the northern hemispheres upcoming season.

The world health organization has made their recommendation for the 2017 southern hemisphere influenza vaccine. Further antigenic and genetic characteristics of recent seasonal influenza viruses are described below and in the full report of the recommendation 1. Influenza activity appeared to be at lower levels than expected for this period. At least 1 component of the southern hemisphere vaccine composition recommendations matched a predominant antigenic characterization in south america in 93%, 95% ci 79%106% of 14 influenza seasons that occurred during 20012014, and at least 1 component of the northern hemisphere vaccine composition recommendations matched a. Influenza b viruses circulated less widely across south america. In the united states, low levels of seasonal influenza activity were detected. In the united states, flu season occurs in the fall and winter.

Recommended composition of influenza virus vaccines for use in the 2020 southern hemisphere influenza season. Influenza seasonality in the tropics and subtropics when. Flu season early spike in southern hemisphere medscape. In the temperate regions of the southern hemisphere, influenza activity typically occurs during april september. There is ongoing discussion on whether the subtropical regions should follow the northern or southern hemisphere seasonal influenza vaccine composition, and when is the best time for vaccination. Following a severe winter epidemic of drifted influenza ah3n2 during januarymarch 2015, the hong kong government purchased vaccines of southern hemisphere formulation for administration prior. However, there was a marginal increase in influenzalike. It is recommended that quadrivalent vaccines for use in the 201819 northern hemisphere influenza season contain the following. Recommended composition of influenza virus vaccines for use in the 2015 southern hemisphere influenza season 25 september 2014 it is recommended that trivalent vaccines for use in the 2015 influenza season southern hemisphere winter contain the following. Who panel changes 2 strains in southern hemisphere flu vaccine. In birds, humans, and pigs, the virus has mutated into many strains.

Puigbarbera j, natividadsancho a, trushakova s, sominina a, pisareva m, ciblak ma, et al. Who recommendations for influenza virus vaccine composition. Historical annual reformulations of the influenza vaccine wikipedia. For countries in equatorial regions, epidemiological considerations influence which recommendation february or september individual national and regional authorities consider appropriate. Historical annual reformulations of the influenza vaccine. Antigenic analysis revealed that all of the ah1n1pdm09 isolates circulating in cambodia during 2012. May 07, 2015 2015 southern hemisphere seasonal influenza vaccination programme to be launched with photo the controller of the centre for health protection chp of the department of health dh, dr leung tinghung, today may 7 announced that the 2015 southern hemisphere seasonal influenza vaccination sh siv programme will be launched tomorrow may 8. Oct 03, 2017 two components, for influenza ah3n2 and b viruses of the vaccine recommended for the southern hemisphere, were changed in comparison with the southern hemisphere 2017 influenza season. In the southern hemisphere for the 20102015 seasons, negative interference from prior seasons vaccination should have been pronounced in 2012 following 3 consecutive seasons of homologous aperth162009h3n2like vaccine and dominant. It is recommended that trivalent vaccines contain the following. Since 1999, the world health organization who has issued annual recommendations for influenza vaccine formulations. Epidemiology of hospital admissions with influenza during the 202014 northern hemisphere influenza season.

Cdc has antigenically andor genetically characterized 933 influenza viruses collected since october 1, 2014, including 27 influenza a h1n1pdm09, 752 influenza a. The person was infected with an influenza a h1n1 variant h1n1v virus and died from complications as a result of the inf ection. Review of the 2015 influenza season in the southern hemisphere. In the northern hemisphere, the flu season can begin as early as october and can last as late as april or may. The influenza season mainly occurs from june to september. Who made its recommendations for the 2015 southern hemisphere influenza vaccine on september 25, 2014, by which time these drifted h3n2 viruses were common, prompting a recommended change in the upcoming. In years in which h3n2 is the predominant strain, there are more hospitalizations. Determination of predominance of influenza virus strains in. Who recommended composition of influenza virus vaccines.

Annual study to investigate inactivated subunit influenza vaccine due to new virus strains for the southern hemisphere 2015 season the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Immunogenicity and safety of southern hemisphere inactivated. In australia, the flu season is considered may to october. Recommended composition of the australian influenza. Influenza in the subtropics is characterized with yearlong circulation of viruses. Whoeurope who releases recommendations for the 2019. Influenza activity continues to decrease across the state of texas. Sep 24, 2015 for quadrivalent vaccines that contain a second b strain, the agency recommended adding phuket307320like virus, a yamagata lineage virus that was the b component of trivalent vaccines for the southern hemisphere s current season and is the b component of trivalent vaccines for the northern hemisphere s upcoming season. While the beginning of major flu activity in each season varies by location, in any. Although influenza activity at the time of writing was low, circulating b viruses were predominantly victoria lineage and h3 viruses were predominantly from genetic group 3c. Who recommendations for influenza virus vaccine composition for. Worldwide, influenza activity during may 24september 5, 2015, was elevated in the temperate southern hemisphere and tropical regions, compared with their levels outside the usual influenza season. Intention to receive influenza vaccination prior to the. Original article by the brazilian journal of infectious diseases.

Circulating influenza ah3n2 viruses were most commonly identified as clade 3c. Vaccination is particularly important for persons at high risk for serious influenzarelated complications and their close. Annual study to investigate inactivated subunit influenza. For quadrivalent vaccines that contain a second b strain, the agency recommended adding phuket307320like virus, a yamagata lineage virus that was the b component of trivalent vaccines for the southern hemisphere s current season and is the b component of trivalent vaccines for the northern hemisphere s upcoming season. The vaccine viruses recommended for inclusion in the 201617 northern hemisphere influenza vaccines are the same vaccine viruses that were.

Influenza ah3n2 and b activity continued in south china. Discussion on use of 2015 sh siv in hk winter seasonal influenza season arrived since end of december 2014 the predominating virus was an antigenically drifted h3n2 virus strain, which can negatively impact effectiveness of vaccine currently used 2015 southern hemisphere sh seasonal influenza vaccine. Efficacy, immunogenicity, and safety of a quadrivalent. This page contains details of the recommended vaccine for the 2015 southern hemisphere influenza season.